Pharmacogenomics An Introduction and Clinical Perspective by Joseph S. Bertino

No critic rating

Waiting for minimum critic reviews

Synopsis

A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS

The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties.

FEATURES

Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
 

About Joseph S. Bertino

See more books from this Author
Joseph S. Bertino Jr., Pharm.D. is an Associate ProfessorJoseph S. Bertino Jr., Pharm.D. is an Associate Professor of Clinical Pharmacology in Medicine at the College of Phys of Clinical Pharmacology in Medicine at the College of Physicians and Surgeons, Columbia University, New York, NY. His icians and Surgeons, Columbia University, New York, NY. His research interests are varied and include work with vaccinesresearch interests are varied and include work with vaccines, antimicrobial pharmacokinetics and pharmacodynamics, treat, antimicrobial pharmacokinetics and pharmacodynamics, treatment of hypertension, pharmacogenetics and pharmacogenomics.ment of hypertension, pharmacogenetics and pharmacogenomics. Dr. Bertino received the Pharm.D. degree from SUNY at Buffa Dr. Bertino received the Pharm.D. degree from SUNY at Buffalo. He has published over 100 original research papers, revilo. He has published over 100 original research papers, review articles and book chapters. His publications have includeew articles and book chapters. His publications have included work in the area of antimicrobial pharmacokinetics, pharmad work in the area of antimicrobial pharmacokinetics, pharmacodynamics and toxicity, drug-drug interactions, general clicodynamics and toxicity, drug-drug interactions, general clinical pharmacology, vaccine pharmacology and the applicationnical pharmacology, vaccine pharmacology and the application of pharmacogenetics to the drug development process. Jos of pharmacogenetics to the drug development process. Joseph D. Ma, PharmD is an Assistant Professor at the Universiteph D. Ma, PharmD is an Assistant Professor at the University of California San Diego, Skaggs School of Pharmacy and Phay of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences. He received his Pharmacy Doctorate frormaceutical Sciences. He received his Pharmacy Doctorate from the University of California, San Francisco. He then complm the University of California, San Francisco. He then completed a 2-year fellowship in clinical pharmacology at Bassetteted a 2-year fellowship in clinical pharmacology at Bassett Healthcare, Cooperstown, NY. Upon fellowship completion, Dr Healthcare, Cooperstown, NY. Upon fellowship completion, Dr. Ma was employed at Amgen, Inc. and was responsible for pha. Ma was employed at Amgen, Inc. and was responsible for phase I protocol development and study operational and managerise I protocol development and study operational and managerial functions. Dr. Ma joined UCSD in 2007. He serves as co-coal functions. Dr. Ma joined UCSD in 2007. He serves as co-coordinator for the winter quarter Therapeutics course and forordinator for the winter quarter Therapeutics course and for a spring quarter elective titled Drug Discovery, Developmen a spring quarter elective titled Drug Discovery, Development, and Commercialization. His research interests are in examt, and Commercialization. His research interests are in examining pharmacokinetic and pharmacodynamic variability and inining pharmacokinetic and pharmacodynamic variability and in the optimization of drugs as probes to phenotype drug-metab the optimization of drugs as probes to phenotype drug-metabolizing enzyme activity. Angela Kashuba, PharmD is an Assolizing enzyme activity. Angela Kashuba, PharmD is an Associate Professor of Pharmacy at the University of North Caroociate Professor of Pharmacy at the University of North Carolina in Chappel Hill. Ms. Kashuba received two grants speciflina in Chappel Hill. Ms. Kashuba received two grants specifically on pharmcgenomics on the elderly. C. Lindsay DeVanically on pharmcgenomics on the elderly. C. Lindsay DeVane, Pharm.D. is Professor of Psychiatry and Behavioral Science, Pharm.D. is Professor of Psychiatry and Behavioral Sciences and Vice Chair for Research in the Department of Psychiates and Vice Chair for Research in the Department of Psychiatry at the Medical University of South Carolina (MUSC) in Chary at the Medical University of South Carolina (MUSC) in Charleston, SC. He directs the Laboratory of Drug Disposition arleston, SC. He directs the Laboratory of Drug Disposition and Pharmacogenetics in the Darby Children's Research Institund Pharmacogenetics in the Darby Children's Research Institute and oversees operation of the core laboratories of MUSC'ste and oversees operation of the core laboratories of MUSC's General Clinical Research Center. Professor Uwe Fuhr MD, General Clinical Research Center. Professor Uwe Fuhr MD, is Clinical Pharmacologist at University of Cologne, Cologn is Clinical Pharmacologist at University of Cologne, Cologne, Germany, Faculty of Medicine. He is a native of Saarbruece, Germany, Faculty of Medicine. He is a native of Saarbruecken, Germany, and attended Johann Wolfgang Goethe Universityken, Germany, and attended Johann Wolfgang Goethe University in Frankfurt am Main, Germany, as an undergraduate in Medic in Frankfurt am Mai
 
Published October 9, 2012 by McGraw-Hill Professional. 288 pages
Genres: Health, Fitness & Dieting, Professional & Technical. Non-fiction

Rate this book!

Add Review
×